The blowback feature in the neck and specially designed bottom radius, for added strength, are important for lyophilization applications. The clear vials are manufactured from low extractable borosilicate glass that conforms to ASTM Type I, Class A and USP Type I requirements. The amber vials are manufactured from low extractable borosilicate glass that conforms to USP Type I requirements. Vials are packaged in shrink-wrapped modules to greatly reduce particulate contamination.